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Inflammation – Vascular Response Transient vasoconstriction -> vasodilatation of arterioles -> hyperaemia ( ->rubor, calor) Arteriolar dilatation occurs after vasoconstriction and results in an opening of the microvascular bed….
Irreversible Cell Injury: Features of irreversible cell injury include Damage to cell membrane : It results due to continued influx of water, loss of membrane phospholipids and loss…
Hemodynamics In a normal blood vessel like capillary, there are two forces acting on the fluid in the circulation. The hydrostatic pressure causes fluid movement from inside the vessel…
Necrosis and Apoptosis The type of necrosis is dependent on the nature, intensity and duration of the injurious agent, and the type of cell involved. Note that initial membrane…
Phases of Wound Healing The entire wound healing process is a complex series of events that begins at the moment of injury and can continue for months to years….
Abnormal Bleeding and Coagulopathies Resuscitation of the bleeding patient with isotonic saline solutions will rapidly dilute and deplete the clotting system. In patients who respond to fluids but appear…
Burn wounds can be categorized into superficial, partial-thickness, and full-thickness injuries to skin, depending on depth of injury to the epidermis and dermis. The severity of a burn is…