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Inflammation – Vascular Response
Transient vasoconstriction -> vasodilatation of arterioles -> hyperaemia ( ->rubor, calor)
Arteriolar dilatation occurs after vasoconstriction and results in an opening of the microvascular bed. Increased blood flow to the injured area is called hyperaemia and causes redness and heat – note also that there is an increase in the net pressure in capillaries and post capillary venules, leading to an outflow of fluid.
Direct injury to vessels (or venule endothelial cell contraction) causes alteration of vessel permeability, leading to leakage of fluid and plasma proteins:
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