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Factors Controlling the Bacterial Penetration at tooth Restoration Gaps 1) Size and Nature of Gap – Size- Range (10-50 μm) – Nature- Self sealing ability of restorative material (deposition of mineral salts of low solubility in the space, accumulation of corrosion products, calcification of the plaque like debris around the margins and etc.) 2) Host defence – Sclerosis of Dentinal tubules – Reparative Dentine – The hydrostatic pressure of the pulp is higher compared to the outside pressure of the oral cavity. This pressure difference moves the dentinal fluid outwards which opposes the bacteria and their products moving inwards, though only to a negligible extent. – Some plasma proteins in the dentinal fluid may act as antibacterial substances and large molecular weight proteins like fibrinogen make dentin less permeable to bacteria. 3) Restorations – GIC, Composites, Compomers etc. release fluorides in gaps
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Lysosomes Lysosomes in animal cells are bounded by a single membrane. They have an acidic internal pH (pH 4–5), maintained by proteins in the membrane that pump in Hions….
Medial Surface of the Parietal Lobe This surface of the parietal lobe contains a portion of the cingulate gyrus and the medial extension of the postcentral gyrus. It is…
Inflammation – Vascular Response Transient vasoconstriction -> vasodilatation of arterioles -> hyperaemia ( ->rubor, calor) Arteriolar dilatation occurs after vasoconstriction and results in an opening of the microvascular bed….